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Article

MEN1 gene and its mutations: basic and clinical implications.

Cancer science - 1 Feb 2009

Tsukada Toshihiko, Nagamura Yuko, Ohkura Naganari

Abstract excerpt

Heterozygous germline mutations of the tumor-suppressor gene MEN1 are responsible for multiple endocrine neoplasia type 1 (MEN1), a dominantly inherited familial cancer syndrome characterized by pituitary, parathyroid, and enteropancreatic tumors. Various mutations have been identified throughout the entire gene region in patients with MEN1 and related disorders. Neither mutation hot spot nor phenotype–genotype...

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Source

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Identifiers

PMID: 19068082
DOI: 10.1111/j.1349-7006.2008.01034.x
PMCID: PMC11159991

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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