p53 mutation and detection of p53 protein expression in oral leukoplakia and oral squamous cell carcinoma.

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Article

p53 mutation and detection of p53 protein expression in oral leukoplakia and oral squamous cell carcinoma.

Anticancer research - 1 Jan 2000

Ries J C, Schreiner D, Steininger H, Girod S C

Abstract excerpt

In many studies the detection of p53 protein by immunohistochemistry (IHC) with one antibody is assumed to be consistent with a mutation of the gene. To determine the correlation of protein detection by immunohistochemistry and gene mutation, paraffin embedded specimens of 60 oral leukoplakias (O...

Topics

Antibodies, Monoclonal
Carcinoma, Squamous Cell
Gene Expression
Genes, p53
Humans
Immunohistochemistry
Leukoplakia, Oral
Mouth Neoplasms
Mutation
Paraffin Embedding
Polymorphism, Single-Stranded Conformational
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 9677462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9677462-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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