Article
Localized enhancement and repression of the activity of the TGF-beta family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo.
Development (Cambridge, England) - 1 Mar 1992
Ferguson E L, Anderson K V
Abstract excerpt
Seven zygotically active genes are required for normal patterning of the dorsal 40% of the Drosophila embryo. Among these genes, decapentaplegic (dpp) has the strongest mutant phenotype: in the absence of dpp, all cells in the dorsal and dorsolateral regions of the embryo adopt fates characteristic of more ventrally derived cells (Irish and Gelbart (1987) Genes Dev. 1, 868-879). Here we describe the phenotypes...
Topics
- Animals
- Drosophila
- Gene Expression Regulation
- Morphogenesis
- Mutation
- Phenotype
- Transforming Growth Factor beta
- Zygote