Article
Requirement of the LIM homeodomain transcription factor tailup for normal heart and hematopoietic organ formation in Drosophila melanogaster.
Molecular and cellular biology - 1 Jun 2007
Tao Ye, Wang Jianbo, Tokusumi Tsuyoshi, Gajewski Kathleen, Schulz Robert A
Abstract excerpt
Dorsal vessel morphogenesis in Drosophila melanogaster serves as a superb system with which to study the cellular and genetic bases of heart tube formation. We used a cardioblast-expressed Toll-GFP transgene to screen for additional genes involved in heart development and identified tailup as a locus essential for normal dorsal vessel formation. tailup, related to vertebrate islet1, encodes a LIM homeodomain...
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