Article
Viral and cellular factors for resistance against antiretroviral agents.
Intervirology - 1 Jan 1997
Gröschel B, Cinatl J, Cinatl J
Abstract excerpt
Long-term treatment of HIV-1-infected patients with antiretroviral agents may result in failure of therapy, due to the rapid emergence of resistant virus mutants with decreased susceptibility to therapeutic agents. However, in addition to viral resistance other factors, i.e. cellular factors, may...
Topics
- Acquired Immunodeficiency Syndrome
- Cell Line
- Drug Resistance, Microbial
- HIV-1
- Humans
- Leukocytes, Mononuclear
- Mutation
- Retroviridae
- Reverse Transcriptase Inhibitors
- Thymidine Kinase
- Zidovudine