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Article

Genetic determinant and environmental carcinogens.

Mutation research - 18 Jun 1998

Nagao M, Ochiai M, Ushijima T, Watanabe M, Sugimura T, Nakagama H

Abstract excerpt

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is the most abundant mutagenic heterocyclic amine (HCA) present in cooked foods. PhIP induces colon cancer in male Fischer 344 (F344) rats, and its role in human colon carcinogenesis has been suspected. To study the ecogenetics in PhIP colon...

Topics

Animals
Carcinogens, Environmental
Colonic Neoplasms
Female
Genotype
Humans
Imidazoles
Male
Mutagens
Polymorphism, Genetic
Rats
Species Specificity

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Identifiers

PMID: 9675250
DOI: 10.1016/s0027-5107(97)00285-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9675250-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Genetic determinant and environmental carcinogens.PMID 9675250Read ↗

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