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Article

Genetic determinant and environmental carcinogens.

Mutation research - 18 Jun 1998

Nagao M, Ochiai M, Ushijima T, Watanabe M, Sugimura T, Nakagama H

Abstract excerpt

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is the most abundant mutagenic heterocyclic amine (HCA) present in cooked foods. PhIP induces colon cancer in male Fischer 344 (F344) rats, and its role in human colon carcinogenesis has been suspected. To study the ecogenetics in PhIP colon carcinogenesis, rat system using aberrant crypt focus (ACF) formation as a phenotypic marker was applied. Among Buffalo...

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Source

Identifiers

PMID: 9675250
DOI: 10.1016/s0027-5107(97)00285-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic determinant and environmental carcinogens.PMID 9675250Read ↗

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