Article
Genetic polymorphisms and susceptibility to cancer development.
Pharmacogenetics - 1 Jan 1995
Sugimura T, Inoue R, Ohgaki H, Ushijima T, Canzian F, Nagao M
Abstract excerpt
Humans show heterogeneous susceptibility to cancer development, suggesting the involvement of various genetic backgrounds in control of the production of endogenous carcinogens, the metabolism of carcinogens, the repair of DNA damage, cell proliferation and defence mechanisms including immune reactions. Gastric cancer is the major cancer in Japan. However, little is known about the genes linked with its...
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