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Modeling human colon cancer in rodents using a food‐borne carcinogen, PhIP

1 Oct 2005

Abstract excerpt

Animal models provide researchers with powerful tools to elucidate multistage mechanisms for cancer development and to gain further insights into the biological roles of various cancer-related genes in in vivo situations. As for colon cancer models in rodents, Apc-disrupted mice, including ApcMin, have been one of the most widely utilized animal models to dissect the molecular events implicated in the development...

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PMID: 16232193
DOI: 10.1111/j.1349-7006.2005.00107.x

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