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Article

Leukoregulin induction of protein expression in human orbital fibroblasts: Evidence for anatomical site-restricted cytokine–target cell interactions

21 Jul 1998

Abstract excerpt

The molecular basis for the profound inflammatory response and the accumulation of hyaluronan in orbital connective tissues seen in thyroid-associated ophthalmopathy is unknown. Moreover, the link between the orbital manifestations of Graves' disease and those in the pretibial skin, localized dermopathy, has yet to be established. We have reported recently that leukoregulin, an activated T lymphocyte-derived...

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PMID: 9671777
DOI: 10.1073/pnas.95.15.8904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Leukoregulin induction of protein expression in human orbital fibroblasts: Evidence for anatomical site-restricted cytokine–target cell interactionsPMID 9671777Read ↗

IL-1β Induces IL-6 Expression in Human Orbital Fibroblasts: Identification of an Anatomic-Site Specific Phenotypic Attribute Relevant to Thyroid-Associated OphthalmopathySemantic proximity Read ↗

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Orbital fibroblast heterogeneity may determine the clinical presentation of thyroid-associated ophthalmopathy.Semantic proximity Read ↗

Orbital Fibroblast Heterogeneity May Determine the Clinical Presentation of Thyroid-Associated OphthalmopathySemantic proximity Read ↗

Prostaglandin E2 elicits a morphological change in cultured orbital fibroblasts from patients with Graves ophthalmopathy.Semantic proximity Read ↗

Induction by IL-1β of Tissue Inhibitor of Metalloproteinase-1 in Human Orbital Fibroblasts: Modulation of Gene Promoter Activity by IL-4 and IFN-γSemantic proximity Read ↗

Characterization of adhesion receptors on cultured microvascular endothelial cells derived from the retroorbital connective tissue of patients with Grave's ophthalmopathy.Semantic proximity Read ↗

Current perspectives on the role of orbital fibroblasts in the pathogenesis of Graves' ophthalmopathySemantic proximity Read ↗

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Evidence for cellular heterogeneity in primary cultures of human orbital fibroblasts.Semantic proximity Read ↗

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