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Article

Evidence for cellular heterogeneity in primary cultures of human orbital fibroblasts.

The Journal of clinical endocrinology and metabolism - 1 Sept 1995

Smith T J, Sempowski G D, Wang H S, Del Vecchio P J, Lippe S D, Phipps R P

Abstract excerpt

Orbital fibroblasts in culture display phenotypic attributes that distinguish them from fibroblasts derived from other anatomical regions. The current studies were conducted to define potential cellular heterogeneity among orbital fibroblasts with regard to 1) differential expression of Thy-1, a 25-kilodalton glycoprotein associated with cell signaling; 2) cells undergoing a change in shape in response to...

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Identifiers

PMID: 7673404
DOI: 10.1210/jcem.80.9.7673404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for cellular heterogeneity in primary cultures of human orbital fibroblasts.PMID 7673404Read ↗

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Unique attributes of orbital fibroblasts and global alterations in IGF-1 receptor signaling could explain thyroid-associated ophthalmopathy.Semantic proximity Read ↗

Orbital Fibroblasts Exhibit a Novel Pattern of Responses to Proinflammatory Cytokines: Potential Basis for the Pathogenesis of Thyroid-Associated OphthalmopathySemantic proximity Read ↗

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