Article
Prostaglandin E2 elicits a morphological change in cultured orbital fibroblasts from patients with Graves ophthalmopathy.
Proceedings of the National Academy of Sciences of the United States of America - 24 May 1994
Smith T J, Wang H S, Hogg M G, Henrikson R C, Keese C R, Giaever I
Abstract excerpt
Fibroblasts derived from distinct anatomical regions appear to differ in regard to their behavior in culture. These differences may reflect functions of these cells in vivo that are tissue specific. Moreover, intrinsic differences in fibroblasts may underlie the site-specific connective tissue manifestations associated with systemic disease. We have demonstrated previously that orbital fibroblasts exhibit...
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