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Article

Regulation of TNFalpha and TGFbeta-1 gene transcription by HIV-1 Tat in CNS cells.

Journal of neuroimmunology - 1 Jul 1998

Sawaya B E, Thatikunta P, Denisova L, Brady J, Khalili K, Amini S

Abstract excerpt

Tat is a transcription transactivator produced by the human immunodeficiency virus type 1 (HIV-1) at the early phase of infection and plays a critical role in the expression and replication of the viral genome. This 86 amino acid protein, which can be secreted from the infected cells, has the ability to enter uninfected cells and exert its activity upon the responsive genes. Earlier results indicated that in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9670843
DOI: 10.1016/s0165-5728(98)00044-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of TNFalpha and TGFbeta-1 gene transcription by HIV-1 Tat in CNS cells.PMID 9670843Read ↗

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