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Article

Trans-activation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells.

1 May 1990

Abstract excerpt

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by the JC virus (JCV), a human papovavirus. PML is a relatively rare disease seen predominantly in immunocompromised individuals and is a frequent complication observed in AIDS patients. The significantly higher incidence of PML in AIDS patients than in other immunosuppressive disorders has suggested...

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Identifiers

PMID: 2159152
DOI: 10.1073/pnas.87.9.3479

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Trans-activation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells.PMID 2159152Read ↗

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Rearranged JC Virus Noncoding Control Regions Found in Progressive Multifocal Leukoencephalopathy Patient Samples Increase Virus Early Gene Expression and Replication RateSemantic proximity Read ↗

The transcription factor Sp1 binds to the JC virus promoter and is selectively expressed in glial cells in human brainSemantic proximity Read ↗

Functional Interaction between JC Virus Late Regulatory Agnoprotein and Cellular Y-Box Binding Transcription Factor, YB-1Semantic proximity Read ↗

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