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Article

p73 Interacts with human immunodeficiency virus type 1 Tat in astrocytic cells and prevents its acetylation on lysine 28.

Molecular and cellular biology - 1 Sept 2005

Amini Shohreh, Mameli Giuseppe, Del Valle Luis, Skowronska Anna, Reiss Krzysztof, Gelman Benjamin B, White Martyn K, Khalili Kamel, Sawaya Bassel E

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) Tat is a potent transcriptional activator of the HIV-1 promoter and also has the ability to modulate a number of cellular regulatory circuits including apoptosis. Tat exerts its effects through interaction with viral as well as cellular proteins. Here, we studied the influence of p73, a protein that is implicated in apoptosis and cell cycle control, on Tat functions in...

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Share to Acetyltransferases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Products, tat

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Share to tat Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 16135803
DOI: 10.1128/MCB.25.18.8126-8138.2005
PMCID: PMC1234304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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