Inverse association between cyclin D1 overexpression and retinoblastoma gene mutation in thyroid carcinomas.

doi:10.1385/ENDO:8:1:61

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Article

Inverse association between cyclin D1 overexpression and retinoblastoma gene mutation in thyroid carcinomas.

Endocrine - 1 Feb 1998

Zou M, Shi Y, Farid N R, al-Sedairy S T

Abstract excerpt

Cyclin D1 plays a key role in the regulation of the G1/S transition through the cell cycle. Deregulation of cyclin D1, most often leading to overexpression of the gene, has been reported in many tumor types. It has been suggested that cyclin D1 overexpression could be an alternative mechanism for...

Topics

Adenocarcinoma, Follicular
Adult
Aged
Blotting, Northern
Blotting, Southern
Carcinoma
Carcinoma, Papillary
Cyclin D1
Female
Gene Expression
Genes, Retinoblastoma
Goiter, Nodular
Humans
Male
Middle Aged
Mutation
Thyroid Neoplasms

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