Article
A genome-wide search for human type 1 diabetes susceptibility genes.
Nature - 8 Sept 1994
Davies J L, Kawaguchi Y, Bennett S T, Copeman J B, Cordell H J, Pritchard L E, Reed P W, Gough S C, Jenkins S C, Palmer S M
Abstract excerpt
We have searched the human genome for genes that predispose to type 1 (insulin-dependent) diabetes mellitus using semi-automated fluorescence-based technology and linkage analysis. In addition to IDDM1 (in the major histocompatibility complex on chromosome 6p21) and IDDM2 (in the insulin gene region on chromosome 11p15), eighteen different chromosome regions showed some positive evidence of linkage to disease....
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