Article
Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8.
Human molecular genetics - 1 May 1996
Luo D F, Buzzetti R, Rotter J I, Maclaren N K, Raffel L J, Nisticò L, Giovannini C, Pozzilli P, Thomson G, She J X
Abstract excerpt
Previous genome-wide mapping studies have provided suggestive linkage evidence for several novel susceptibility loci responsible for insulin-dependent diabetes mellitus (IDDM); however, the evidence was not sufficient to confirm the existence of these genes. We analyzed 265 Caucasian families with IDDM and report the first evidence that meets the standard for confirmed linkage for three susceptibility loci. The...
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