Article
Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8.
Human molecular genetics - 1 May 1996
Luo D F, Buzzetti R, Rotter J I, Maclaren N K, Raffel L J, Nisticò L, Giovannini C, Pozzilli P, Thomson G, She J X
Abstract excerpt
Previous genome-wide mapping studies have provided suggestive linkage evidence for several novel susceptibility loci responsible for insulin-dependent diabetes mellitus (IDDM); however, the evidence was not sufficient to confirm the existence of these genes. We analyzed 265 Caucasian families wit...
Topics
- Adult
- Child
- Chromosomes, Human, Pair 11
- Diabetes Mellitus, Type 1
- Female
- Genetic Linkage
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Microsatellite Repeats