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Article

Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27.

American journal of human genetics - 1 Oct 1995

Luo D F, Bui M M, Muir A, Maclaren N K, Thomson G, She J X

Abstract excerpt

Affected-sib-pair analyses were performed using 104 Caucasian families to map genes that predispose to insulin-dependent diabetes mellitus (IDDM). We have obtained linkage evidence for D6S446 (maximum lod score [MLS] = 2.8) and for D6S264 (MLS = 2.0) on 6q25-q27. Together with a previously report...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 15
Chromosomes, Human, Pair 6
DNA, Satellite
Diabetes Mellitus, Type 1
Genetic Heterogeneity
Genetic Linkage
Genetic Predisposition to Disease
Humans
Lod Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nuclear Family

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Open in PubMed Open full text

Identifiers

PMID: 7573053
PMCID: PMC1801491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7573053-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Related research

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Click a neighbor to travelStep 1 · 12 closest

Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27.PMID 7573053Read ↗

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Physical and genetic mapping of IDDM8 on chromosome 6q27.Semantic proximity Read ↗

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A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus.Semantic proximity Read ↗

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Evidence of a non-MHC susceptibility locus in type I diabetes linked to HLA on chromosome 6.Semantic proximity Read ↗

A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions.Semantic proximity Read ↗

Fine-mapping of the type 1 diabetes locus (IDDM4) on chromosome 11q and evaluation of two candidate genes (FADD and GALN) by affected sibpair and linkage-disequilibrium analyses.Semantic proximity Read ↗

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