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Article

Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families.

American journal of human genetics - 1 Oct 2001

Cox N J, Wapelhorst B, Morrison V A, Johnson L, Pinchuk L, Spielman R S, Todd J A, Concannon P

Abstract excerpt

Type 1 diabetes (T1D) is a genetically complex disorder of glucose homeostasis that results from the autoimmune destruction of the insulin-secreting cells of the pancreas. Two previous whole-genome scans for linkage to T1D in 187 and 356 families containing affected sib pairs (ASPs) yielded apparently conflicting results, despite partial overlap in the families analyzed. However, each of these studies...

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Identifiers

PMID: 11507694
DOI: 10.1086/323501
PMCID: PMC1226067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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