Article
p59fyn and pp60c-src modulate axonal guidance in the developing mouse olfactory pathway.
Journal of neurobiology - 1 Jul 1998
Morse W R, Whitesides J G, LaMantia A S, Maness P F
Abstract excerpt
The Src-family tyrosine kinases p59fyn and pp60c-src are localized on axons of the mouse olfactory nerve during the initial stages of axonal growth, but their functional roles remain to be defined. To study the role of these kinases, we analyzed the trajectory of the olfactory nerve in E11.5 homozygous null mutant mice lacking single src or fyn gens and double mutants lacking both genes. Primary olfactory axons...
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