Article
Complete protein linkage map of poliovirus P3 proteins: interaction of polymerase 3Dpol with VPg and with genetic variants of 3AB.
Journal of virology - 1 Aug 1998
Xiang W, Cuconati A, Hope D, Kirkegaard K, Wimmer E
Abstract excerpt
Poliovirus has evolved to maximize its genomic information by producing multifunctional viral proteins. The P3 nonstructural proteins harbor various activities when paired with different binding partners. These viral polypeptides regulate host cell macromolecular synthesis and function as protein...
Topics
- Amino Acid Sequence
- DNA-Directed RNA Polymerases
- Genetic Variation
- Molecular Sequence Data
- Protein Binding
- Protein Precursors
- RNA-Dependent RNA Polymerase
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Viral Core Proteins
- Viral Nonstructural Proteins