Article
Interaction of foot-and-mouth disease virus nonstructural protein 3A with host protein DCTN3 is important for viral virulence in cattle.
Journal of virology - 1 Mar 2014
Gladue D P, O'Donnell V, Baker-Bransetter R, Pacheco J M, Holinka L G, Arzt J, Pauszek S, Fernandez-Sainz I, Fletcher P, Brocchi E, Lu Z, Rodriguez L L, Borca M V
Abstract excerpt
UNLABELLED: Nonstructural protein 3A of foot-and-mouth disease virus (FMDV) is a partially conserved protein of 153 amino acids in most FMDVs examined to date. The role of 3A in virus growth and virulence within the natural host is not well understood. Using a yeast two-hybrid approach, we identi...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Cattle
- Cell Line
- Dynactin Complex
- Foot-and-Mouth Disease
- Foot-and-Mouth Disease Virus
- Gene Expression
- Humans
- Intracellular Space
- Microtubule-Associated Proteins
- Molecular Sequence Data