Genetic dissection of interaction between poliovirus 3D polymerase and viral protein 3AB.

doi:10.1128/JVI.71.12.9490-9498.1997

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Article

Genetic dissection of interaction between poliovirus 3D polymerase and viral protein 3AB.

Journal of virology - 1 Dec 1997

Hope D A, Diamond S E, Kirkegaard K

Abstract excerpt

Poliovirus RNA-dependent RNA polymerase 3D and viral protein 3AB are both thought to be required for the initiation of RNA synthesis. These two proteins physically associate with each other and with viral RNA replication complexes found on virus-induced membranes in infected cells. An understandi...

Topics

Alleles
Cell Membrane
DNA-Directed RNA Polymerases
Defective Viruses
HeLa Cells
Humans
Mutagenesis
Nucleic Acid Hybridization
Phenotype
Poliovirus
RNA, Viral
RNA-Dependent RNA Polymerase
Recombinant Fusion Proteins
Temperature
Valine
Viral Core Proteins

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