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Article

Genetic dissection of interaction between poliovirus 3D polymerase and viral protein 3AB.

Journal of virology - 1 Dec 1997

Hope D A, Diamond S E, Kirkegaard K

Abstract excerpt

Poliovirus RNA-dependent RNA polymerase 3D and viral protein 3AB are both thought to be required for the initiation of RNA synthesis. These two proteins physically associate with each other and with viral RNA replication complexes found on virus-induced membranes in infected cells. An understanding of the interface between 3D and 3AB would provide a first step in visualizing the architecture of the multiprotein...

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Identifiers

PMID: 9371611
DOI: 10.1128/JVI.71.12.9490-9498.1997
PMCID: PMC230255

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