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Article

A mutant baculovirus with a temperature-sensitive IE-1 transregulatory protein.

Journal of virology - 1 Feb 1994

Ribeiro B M, Hutchinson K, Miller L K

Abstract excerpt

We have mapped the mutation responsible for the temperature-sensitive (ts) phenotype of tsB821, a mutant of the baculovirus Autographa californica nuclear polyhedrosis virus (H. H. Lee and L. K. Miller, J. Virol. 31:240-252, 1979), to a single nucleotide which changes alanine 432 of the multifunctional regulatory protein IE-1 to a valine. Mapping was done with a combination of marker rescue and transient...

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Identifiers

PMID: 8289337
DOI: 10.1128/JVI.68.2.1075-1084.1994
PMCID: PMC236546

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