Article
Coronary thrombosis and the platelet glycoprotein IIIA gene PLA2 polymorphism.
Thrombosis and haemostasis - 1 Aug 1998
Durante-Mangoni E, Davies G J, Ahmed N, Ruggiero G, Tuddenham E G
Abstract excerpt
Myocardial infarction results from a platelet-rich occlusive coronary thrombus. Platelet membrane glycoprotein IIb/IIIa plays an important role in platelet adhesion and aggregation. Two polymorphisms of the gene encoding the IIIa subunit. PLA1 and PLA2, have been identified. We investigated the f...
Topics
- Adult
- Alleles
- Angina Pectoris
- Coronary Thrombosis
- Humans
- Middle Aged
- Myocardial Infarction
- Platelet Glycoprotein GPIIb-IIIa Complex
- Polymorphism, Genetic
- Risk Factors
- Survivors
