Article
Coronary thrombosis and the platelet glycoprotein IIIA gene PLA2 polymorphism.
Thrombosis and haemostasis - 1 Aug 1998
Durante-Mangoni E, Davies G J, Ahmed N, Ruggiero G, Tuddenham E G
Abstract excerpt
Myocardial infarction results from a platelet-rich occlusive coronary thrombus. Platelet membrane glycoprotein IIb/IIIa plays an important role in platelet adhesion and aggregation. Two polymorphisms of the gene encoding the IIIa subunit. PLA1 and PLA2, have been identified. We investigated the frequency of these polymorphisms in 114 consecutive patients with a history of angina-like chest pain admitted for...
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