Article
Assessment of the role of activator protein-1 on transcription of the mouse steroidogenic acute regulatory protein gene.
Molecular endocrinology (Baltimore, Md.) - 1 Mar 2004
Manna Pulak R, Eubank Darrell W, Stocco Douglas M
Abstract excerpt
cAMP-dependent mechanisms regulate the steroidogenic acute regulatory (StAR) protein even though its promoter lacks a consensus cAMP response-element (CRE, TGACGTCA). Transcriptional regulation of the StAR gene has been demonstrated to involve combinations of DNA sequences that provide recognition motifs for sequence-specific transcription factors. We recently identified and characterized three canonical 5'-CRE...
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