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Article

Suppression of inhibitory GABAergic transmission by cAMP signaling pathway: alterations in learning and memory mutants.

The European journal of neuroscience - 1 May 2013

Ganguly Archan, Lee Daewoo

Abstract excerpt

The cAMP signaling pathway mediates synaptic plasticity and is essential for memory formation in both vertebrates and invertebrates. In the fruit fly Drosophila melanogaster, mutations in the cAMP pathway lead to impaired olfactory learning. These mutant genes are preferentially expressed in the mushroom body (MB), an anatomical structure essential for learning. While cAMP-mediated synaptic plasticity is known to...

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Identifiers

PMID: 23387411
DOI: 10.1111/ejn.12144
PMCID: PMC3648628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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