Article
Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer.
British journal of cancer - 1 Jun 1998
Masramon L, Arribas R, Tórtola S, Perucho M, Peinado M A
Abstract excerpt
C-myc gene activation is a common event in multiple types of neoplasia and has been associated with different cellular processes relevant to the malignant transformation of cancer cells. C-myc gene amplification has been analysed in colorectal carcinomas by means of an innovative DNA fingerprinti...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Colorectal Neoplasms
- DNA Fingerprinting
- DNA Primers
- DNA, Neoplasm
- Female
- Gene Amplification
- Gene Expression Regulation, Neoplastic
- Genes, myc
- Genes, p53
- Humans
- Male
- Middle Aged
- Mutation
- Neoplasm Staging