Article
Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer.
British journal of cancer - 1 Jun 1998
Masramon L, Arribas R, Tórtola S, Perucho M, Peinado M A
Abstract excerpt
C-myc gene activation is a common event in multiple types of neoplasia and has been associated with different cellular processes relevant to the malignant transformation of cancer cells. C-myc gene amplification has been analysed in colorectal carcinomas by means of an innovative DNA fingerprinting method based on the arbitrarily primed PCR. This method requires a low amount of DNA, uses multiple internal...
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