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Article

Overexpression and Amplification of c-myc during Progression of Human Colorectal Cancer

30 Jun 2009

Abstract excerpt

Overexpression and amplification of the c-myc oncogene occur in approximately 70 and 10% of human primary colorectal carcinomas, respectively, indicating the importance of this gene in colorectal tumorigenesis. Little, however, is known about the involvement of c-myc in the progression of colorectal cancer. We therefore determined c-myc gene expression and amplification in a group of primary tumors and metastases...

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Identifiers

PMID: 8960139
DOI: 10.1159/000227619

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