Article
DNA replication is completed in Saccharomyces cerevisiae cells that lack functional Cdc14, a dual-specificity protein phosphatase.
Molecular & general genetics : MGG - 1 May 1998
Fitzpatrick P J, Toyn J H, Millar J B, Johnston L H
Abstract excerpt
The Cdc14 protein encodes a dual-specificity protein phosphatase which functions in late mitosis, and considerable genetic evidence suggests a role in DNA replication. We find that cdc14 mutants arrested in late mitosis maintain persistent levels of mitotic kinase activity, suggesting that Cdc14...
Topics
- Cell Cycle Proteins
- Cloning, Molecular
- Cyclin-Dependent Kinase Inhibitor Proteins
- DNA Replication
- DNA, Fungal
- Enzyme Inhibitors
- Fungal Proteins
- Mutation
- Phosphoprotein Phosphatases
- Protein Tyrosine Phosphatases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Temperature