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Article

Evidence for the presence of insulin-dependent diabetes-associated alleles on the distal part of mouse chromosome 6.

Genome research - 1 Jun 1998

Melanitou E, Joly F, Lathrop M, Boitard C, Avner P

Abstract excerpt

Type 1 diabetes (IDDM) is a complex disorder with multifactorial and polygenic etiology. A genome-wide screen performed in a BC1 cohort of a cross between the nonobese diabetic (NOD) mouse with the diabetes-resistant feral strain PWK detected a major locus contributing to diabetes development on the distal part of chromosome 6. Unlike the majority of other Idd loci identified in intraspecific crosses,...

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Identifiers

PMID: 9647636
DOI: 10.1101/gr.8.6.608
PMCID: PMC310738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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