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Article

Three loci on mouse chromosome 6 influence onset and final incidence of type I diabetes in NOD.C3H congenic strains.

Genomics - 1 Jun 2001

Rogner U C, Boitard C, Morin J, Melanitou E, Avner P

Abstract excerpt

The development of insulin-dependent diabetes mellitus in both human and mouse is dependent on the interaction between genetic and environmental factors. The analysis of newly created NOD.C3H congenic strains for spontaneous and cyclophosphamide-induced diabetes has allowed the definition of three controlling genetic loci on mouse chromosome 6. A NOD-derived susceptibility allele at the Idd6 locus strongly...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11386752
DOI: 10.1006/geno.2001.6508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Three loci on mouse chromosome 6 influence onset and final incidence of type I diabetes in NOD.C3H congenic strains.PMID 11386752Read ↗

A susceptibility allele from a non-diabetes-prone mouse strain accelerates diabetes in NOD congenic mice.Semantic proximity Read ↗

Evidence for the presence of insulin-dependent diabetes-associated alleles on the distal part of mouse chromosome 6.Semantic proximity Read ↗

Congenic mice reveal genetic epistasis and overlapping disease loci for autoimmune diabetes and listeriosis.Semantic proximity Read ↗

Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice: identification of two potential candidate subloci.Semantic proximity Read ↗

Lrmp and Bcat1 are candidates for the type I diabetes susceptibility locus Idd6.Semantic proximity Read ↗

Mapping by genetic interaction: high-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse.Semantic proximity Read ↗

Colocalization of mouse autoimmune diabetes loci Idd21.1 and Idd21.2 with IDDM6 (human) and Iddm3 (rat).Semantic proximity Read ↗

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Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse chromosome 3.Semantic proximity Read ↗

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