Article
Differentiation of a stem cell line toward a neuronal phenotype.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Jan 1991
Cheun J E, Yeh H H
Abstract excerpt
This study examined the morphology and the development of inward currents in the course of differentiation of a stem cell toward a neuronal phenotype. Using the P19 embryonal cell line, whole-cell current profiles of P19 cells before, during and after retinoic acid-induced differentiation were matched with their morphology as well as with the expression of neuron-specific enolase-like immunoreactivity. Prior to...
Topics
- Animals
- Cell Aggregation
- Cell Differentiation
- Cell Division
- Cell Line
- Cobalt
- Electrophysiology
- Evoked Potentials
- Immunoenzyme Techniques
- Membrane Potentials
- Neurons
