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Article

Na+ channels in cardiac and neuronal cells derived from a mouse embryonal carcinoma cell line.

The Journal of physiology - 1 Dec 1993

Arreola J, Spires S, Begenisich T

Abstract excerpt

1. Cells from a pluripotent murine embryonal carcinoma cell line (P19) were differentiated in vitro into cells with neurone- and cardiac-like phenotypes. Cells treated with 0.5 microM retinoic acid developed into neurone-like cells possessing extensive neurites. Dimethyl sulphoxide treatment (0.5%) produced large, spontaneously contracting cell aggregates with many properties of cardiac cells. 2. The neurone- and...

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Identifiers

PMID: 8145145
DOI: 10.1113/jphysiol.1993.sp019947
PMCID: PMC1160487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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