Article
Disregulation of ocular morphogenesis by lens-specific expression of FGF-3/int-2 in transgenic mice.
Developmental biology - 1 Jun 1998
Robinson M L, Ohtaka-Maruyama C, Chan C C, Jamieson S, Dickson C, Overbeek P A, Chepelinsky A B
Abstract excerpt
FGF-3, originally named int-2, was discovered as an oncogene frequently activated in mammary carcinomas resulting from the chromosomal integration of the mouse mammary tumor virus (MMTV). Int-2 was later designated FGF-3 based on sequence homology with other members of the fibroblast growth facto...
Topics
- Animals
- Aquaporins
- Cell Differentiation
- Crystallins
- Eye
- Eye Proteins
- Fibroblast Growth Factor 3
- Fibroblast Growth Factors
- Gene Expression Regulation, Developmental
- Immunohistochemistry
- In Situ Hybridization
- Lens, Crystalline
- Membrane Glycoproteins
- Mice
- Mice, Transgenic
- Morphogenesis
- Phenotype
- Proto-Oncogene Proteins