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Article

The murine lens: A model to investigate in vivo epithelial–mesenchymal transition

8 May 2017

Abstract excerpt

Epithelial-mesenchymal transition (EMT) produces myofibroblasts that contribute to the formation of fibrotic tissue with an impairment of tissue homeostasis and functionality. The crystalline lens of the eye is a unique transparent and isolated tissue. The lens vesicle becomes isolated from the surface ectoderm, its cells are all contained as they line the inner surface of the lens capsule. Clinically the...

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PMID: 28480986
DOI: 10.1002/dvdy.24518

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