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Article

Isolation of the Pichia pastoris PYC1 gene encoding pyruvate carboxylase and identification of a suppressor of the pyc phenotype.

Yeast (Chichester, England) - 1 May 1998

Menéndez J, Delgado J, Gancedo C

Abstract excerpt

We have cloned and characterized a gene encoding pyruvate carboxylase from the methylotrophic yeast Pichia pastoris. Disruption of this gene produced inability to grow in minimal medium with glucose as carbon source and ammonium as nitrogen source. Growth was possible with aspartate or glutamate...

Topics

Amino Acid Sequence
Base Sequence
Culture Media
Gene Expression Regulation, Fungal
Genes, Suppressor
Molecular Sequence Data
Phenotype
Pichia
Pyruvate Carboxylase
Saccharomyces cerevisiae
Sequence Analysis, DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Suppression, Genetic

Source

Identifiers

PMID: 9639311
DOI: 10.1002/(SICI)1097-0061(199805)14:7<647::AID-YEA269>3.0.CO;2-L

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9639311-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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