Article
How many tumor suppressor genes are involved in human lung carcinogenesis?
Carcinogenesis - 1 Aug 1999
Kohno T, Yokota J
Abstract excerpt
To date, only a limited number of tumor suppressor genes have been identified as being inactivated in lung cancer. The p53 and RB genes are frequently inactivated by genetic alterations such as chromosomal deletions and loss-of-function mutations, while the p16 gene is inactivated not only by gen...
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