Article
Fluoroquinolone resistance and mutation patterns in gyrA and parC genes in Neisseria gonorrhoeae isolates from Shanghai, China.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Feb 2009
Zhang Tiejun, Zhou Xiaoming, Chen Yue, Gu Weiming, Zhang Tao, Jiang Qingwu
Abstract excerpt
In order to study the resistance of Neisseria (N.) gonorrhoeae to the fluoroquinolone and detect mutation patterns of quinolone resistance-determining regions (QRDRs) of clinical isolates in Shanghai, China, a total of 80 clinical isolates of N. gonorrhoeae were consecutively collected from Shanghai. The MIC of fluoroquinolone for the isolates was examined by using the agar dilution method and the mutation...
Topics
- Bacterial Proteins
- China
- DNA Gyrase
- DNA Topoisomerase IV
- Drug Resistance, Bacterial
- Fluoroquinolones
- Gonorrhea
- Humans
- Mutation
- Neisseria gonorrhoeae