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Article

Analysis of quinolone resistance mechanisms in a sparfloxacin-resistant clinical isolate of Neisseria gonorrhoeae.

Sexually transmitted diseases - 1 Oct 1998

Tanaka M, Nakayama H, Haraoka M, Nagafuji T, Saika T, Kobayashi I

Abstract excerpt

BACKGROUND AND OBJECTIVES: Recently, a reduction in the susceptibility of clinical isolates of Neisseria gonorrhoeae to newer fluoroquinolones including sparfloxacin in vitro has been recognized in Japan. The quinolone resistance mechanisms in gonococcal isolates from a patient with clinical fail...

Topics

Adult
Anti-Infective Agents
Drug Resistance, Microbial
Electrophoresis, Gel, Pulsed-Field
Fluoroquinolones
Gonorrhea
Humans
Male
Microbial Sensitivity Tests
Mutation
Neisseria gonorrhoeae
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quinolones

Treatment Failure

Source

Identifiers

PMID: 9800262
DOI: 10.1097/00007435-199810000-00009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9800262-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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