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Article

High occurrence of simultaneous mutations in target enzymes and MtrRCDE efflux system in quinolone-resistant Neisseria gonorrhoeae.

Sexually transmitted diseases - 1 Jun 2004

Dewi Beti Ernawati, Akira Sasaki, Hayashi Hideo, Ba-Thein William

Abstract excerpt

BACKGROUND: Emergence of multidrug-resistant Neisseria gonorrhoeae resulting from new genetic mutations is a serious threat to controlling gonorrhea. GOAL: To determine 1) antimicrobial susceptibilities and the corresponding genetic mutations and 2) the role of MtrRCDE efflux system in gonococcal resistance to fluoroquinolones. STUDY DESIGN: Antimicrobial susceptibility testing and sequence analysis of gyrA,...

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PMID: 15167645
DOI: 10.1097/00007435-200406000-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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