Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease.

doi:10.1212/wnl.50.6.1905

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Article

Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease.

Neurology - 1 Jun 1998

Hollenbach E, Ackermann S, Hyman B T, Rebeck G W

Abstract excerpt

C766T, a polymorphism in exon 3 of the gene for the low-density lipoprotein receptor-related protein (LRP), was found to be associated with late-onset Alzheimer's disease (AD). We developed a PCR-restriction enzyme-based assay to analyze this allele in 234 AD patients and 103 controls. We confirm...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Aging
Alleles
Alzheimer Disease
Apolipoproteins E
Child
Exons
Gene Frequency
Genotype
Humans
Low Density Lipoprotein Receptor-Related Protein-1
Middle Aged
Polymorphism, Genetic
Receptors, Immunologic

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Open in PubMed

Identifiers

PMID: 9633759
DOI: 10.1212/wnl.50.6.1905

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9633759-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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