Article
RHD genotyping in weak D phenotypes by multiple polymerase chain reactions.
Transfusion - 1 May 1998
Legler T J, Maas J H, Blaschke V, Malekan M, Ohto H, Lynen R, Bustami N, Schwartz D W, Mayr W R, Köhler M, Panzer S
Abstract excerpt
BACKGROUND: Weak D phenotypes involve a quantitative variation of D. The genomic basis in weak D has been disputed, however. STUDY DESIGN AND METHODS: Five sequence-specific polymerase chain reactions (SSP-PCRs) on exons 2, 5, and 7 of the RHD gene were evaluated in 248 white and 98 Japanese blood donors and compared with the results obtained by amplification of intron 4 and serology. All methods and SSP-PCR...
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