Article
Weak D and DEL alleles detected by routine SNaPshot genotyping: identification of four novel RHD alleles.
Transfusion - 1 Feb 2011
Silvy Monique, Simon Sophie, Gouvitsos Julia, Di Cristofaro Julie, Ferrera Virginie, Chiaroni Jacques, Bailly Pascal
Abstract excerpt
BACKGROUND: Molecular RHD blood group typing is very efficient for managing donors and patients carrying any of the various molecular types of weak D and DEL. The purpose of the work was to develop a multiplex polymerase chain reaction (PCR) SNaPshot assay for simultaneous detection of weak D and DEL alleles that are prevalent in Europeans, Africans, and Asians. STUDY DESIGN AND METHODS: Preliminary profiling was...
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