Article
Genetic selection for resistance or susceptibility to oral tolerance to ovalbumin affects general mechanisms of tolerance induction in mice.
Annals of the New York Academy of Sciences - 1 Dec 2004
Kamphorst Alice O, da Silva Maria F S, da Silva Antônio C, Carvalho Claudia R, Faria Ana Maria C
Abstract excerpt
To study the genes involved in oral tolerance susceptibility, two strains of mice were genetically selected for susceptibility (TS) and resistance (TR) to oral tolerance to ovalbumin by bidirectional breeding. Herein we show that the genetic selection process is restricted neither to ovalbumin nor to oral tolerance. It affected oral tolerance to other proteins, such as casein, and tolerance induced the...
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