Article
Preliminary results corroborating the polygenic control of immunological tolerance.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 1990
da-Silva A C, Massa S, Sant'Anna O A
Abstract excerpt
Tolerance-susceptible (TS) and -resistant (TR) lines of mice are in the process of bidirectional genetic selection starting from a genetically heterogeneous population achieved by the equilibrated intercrossing of eight inbred lines. Mice are intragastrically pretreated and then immunized with he...
Topics
- Animals
- Gene Frequency
- Immune Tolerance
- Mice
- Mice, Inbred Strains
- Phenotype
- Selection, Genetic