Article
Preliminary results corroborating the polygenic control of immunological tolerance.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 1990
da-Silva A C, Massa S, Sant'Anna O A
Abstract excerpt
Tolerance-susceptible (TS) and -resistant (TR) lines of mice are in the process of bidirectional genetic selection starting from a genetically heterogeneous population achieved by the equilibrated intercrossing of eight inbred lines. Mice are intragastrically pretreated and then immunized with hen ovalbumin or bovine serum albumin and the extreme phenotypes are selected for assortative mating. The normal...
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