Effect of genetic modifications by selection for immunological tolerance on fungus infection in mice.

doi:10.1016/s1286-4579(01)01373-9

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Effect of genetic modifications by selection for immunological tolerance on fungus infection in mice.

Microbes and infection - 1 Mar 2001

da Silva A C, Bezerra L M, Aguiar T S, Tavares D, Araujo L M, Pinto C E, Ribeiro O G

Abstract excerpt

Two strains of mice genetically selected for extreme phenotypes of immunological tolerance to ovalbumin, susceptible (TS) and resistant (TR), were experimentally infected with Sporothrix schenckii. The objective was to observe whether the genetic modifications produced by the selection might be associated with interstrain differences in adaptive immune and innate responses to infection. Therefore, we evaluated...

Topics

Animals
Genetic Predisposition to Disease
Hypersensitivity, Delayed
Immune Tolerance
Immunity, Cellular
Interferon-gamma
Lethal Dose 50
Macrophages
Mice
Ovalbumin
Phagocytosis
Selection, Genetic
Sporothrix
Sporotrichosis

Source

Open in PubMed

Identifiers

PMID: 11358715
DOI: 10.1016/s1286-4579(01)01373-9

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Time Factors

Tumor Necrosis Factor-alpha