Article
Acyclovir-resistant varicella-zoster virus: phenotypic and genetic characterization.
Journal of medical virology - 1 Jul 1998
Fillet A M, Dumont B, Caumes E, Visse B, Agut H, Bricaire F, Huraux J M
Abstract excerpt
A man with acquired immunodeficiency syndrome (AIDS) developed zoster of the right arm which was resistant clinically to acyclovir. Varicella-zoster virus (VZV) was cultured from a skin biopsy performed at the beginning of acyclovir therapy (isolate 1) and after its failure (isolate 2). The emergence of acyclovir resistance during treatment was investigated by developing a simple and rapid drug sensitivity assay...
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