Acyclovir-resistant varicella-zoster virus: phenotypic and genetic characterization.

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Article

Acyclovir-resistant varicella-zoster virus: phenotypic and genetic characterization.

Journal of medical virology - 1 Jul 1998

Fillet A M, Dumont B, Caumes E, Visse B, Agut H, Bricaire F, Huraux J M

Abstract excerpt

A man with acquired immunodeficiency syndrome (AIDS) developed zoster of the right arm which was resistant clinically to acyclovir. Varicella-zoster virus (VZV) was cultured from a skin biopsy performed at the beginning of acyclovir therapy (isolate 1) and after its failure (isolate 2). The emergence of acyclovir resistance during treatment was investigated by developing a simple and rapid drug sensitivity assay...

Topics

AIDS-Related Opportunistic Infections
Acyclovir
Adult
Antiviral Agents
Drug Resistance, Microbial
Genes, Viral
Herpes Zoster
Herpesvirus 3, Human
Humans
Male
Microbial Sensitivity Tests
Mutation
Polymerase Chain Reaction
Sequence Analysis, DNA
Thymidine Kinase
Viral Plaque Assay

Source

Open in PubMed

Identifiers

PMID: 9624615

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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