Article
Clinical and virologic characterization of acyclovir-resistant varicella-zoster viruses isolated from 11 patients with acquired immunodeficiency syndrome.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Dec 2001
Saint-Léger E, Caumes E, Breton G, Douard D, Saiag P, Huraux J M, Bricaire F, Agut H, Fillet A M
Abstract excerpt
We studied the clinical resistance to acyclovir of infections with varicella-zoster viruses (VZV) in patients with acquired immunodeficiency syndrome, and we correlated it to virologic analyses. Eleven patients with VZV infections (treated with acyclovir, 30 mg/kg/day, given intravenously, or 4 g/day, given orally) were included in the study because of the failure of 10 days of acyclovir therapy. Susceptibility...
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