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Article

Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors.

International journal of cancer - 15 Apr 1994

Bello M J, Vaquero J, de Campos J M, Kusak M E, Sarasa J L, Saez-Castresana J, Pestana A, Rey J A

Abstract excerpt

Alterations of the short arm of chromosome 1 are recurrently found in cytogenetic analysis of malignant gliomas, and deletions of 1p36-p32 region characterize at least the higher-grade tumors, glioblastoma multiforme. Molecular analysis of tumor-derived and normal genomic DNA from 57 cases of gliomas, using a panel of chromosome 1-specific DNA probes showed LOH in 16 tumors. Allelic losses on 1p were primarily...

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PMID: 8157354
DOI: 10.1002/ijc.2910570207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors.PMID 8157354Read ↗

Identification of two distinct deleted regions on the short arm of chromosome 1 and rare mutation of the CDKN2C gene from 1p32 in oligodendroglial tumors.Semantic proximity Read ↗

Two types of chromosome 1p losses with opposite significance in gliomasSemantic proximity Read ↗

1p36 is a preferential target of chromosome 1 deletions in astrocytic tumours and homozygously deleted in a subset of glioblastomasSemantic proximity Read ↗

Allelic status of chromosome 1 in neoplasms of the nervous system.Semantic proximity Read ↗

Identification of a consistent region of allelic loss on 1p32 in meningiomas: correlation with increased morbidity.Semantic proximity Read ↗

Homozygous Deletions of the <i>CDKN2C</i>/p 18<sup>INK4C</sup> Gene on the Short Arm of Chromosome 1 in Anaplastic OligodendrogliomasSemantic proximity Read ↗

Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss.Semantic proximity Read ↗

Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene.Semantic proximity Read ↗

Oligodendroglial Tumors: Refinement of Candidate Regions on Chromosome Arm 1p and Correlation of 1p/19q Status with SurvivalSemantic proximity Read ↗

Loss of NOTCH2 Positively Predicts Survival in Subgroups of Human Glial Brain TumorsSemantic proximity Read ↗

Deletion mapping of the short arm of chromosome 1 identifies a common region of deletion distal to D1S496 in human meningiomas.Semantic proximity Read ↗

Distinction in gene expression profiles of oligodendrogliomas with and without allelic loss of 1pSemantic proximity Read ↗

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