Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors.

doi:10.1002/ijc.2910570207

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Article

Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors.

International journal of cancer - 15 Apr 1994

Bello M J, Vaquero J, de Campos J M, Kusak M E, Sarasa J L, Saez-Castresana J, Pestana A, Rey J A

Abstract excerpt

Alterations of the short arm of chromosome 1 are recurrently found in cytogenetic analysis of malignant gliomas, and deletions of 1p36-p32 region characterize at least the higher-grade tumors, glioblastoma multiforme. Molecular analysis of tumor-derived and normal genomic DNA from 57 cases of gli...

Topics

Alleles
Chromosome Deletion
Chromosomes, Human, Pair 1
Glioma
Humans
Oligodendroglioma

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